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Mental Wellness
Wellav8 Standard — 4.8/5

Nordic Naturals Ultimate Omega

“The most studied nutrient for depression. In your hands.”

$28supplement

IFOS certified, triglyceride form, 1280mg EPA+DHA. Omega-3 fatty acids are the single most studied nutrient for mood disorders. EPA specifically modulates inflammatory pathways linked to depression. This is where mental wellness supplementation starts.

Our assessment

Purity5/5
Efficacy5/5
Sourcing5/5
Value4/5
Transparency5/5

Purity & verification

Verification & Testing

Third-party tested
GMP certified
Heavy metals free
No proprietary blends
COA available
View Certificate of Analysis →
Contains fishGluten-free

Why we chose it

IFOS certified purity

High EPA ratio for mood support

Triglyceride form for absorption

The foundation of any mental wellness stack

Key ingredients

EPA (650mg)DHA (450mg)

The science

Meta-analyses of 26 RCTs show omega-3s (especially EPA-dominant formulas) significantly reduce depression symptoms. EPA reduces neuroinflammation via resolution of inflammation pathways. DHA supports neuronal membrane fluidity.

Evidence

From the sources we read every week for our concierge recommendations.

  • Rhonda Patrick

    “ FoundMyFitness Topic - Omega-3 fatty acids ”

    Emerging research suggests that optimal human health – especially in populations with low intake – may require substantially higher intake than current standards of adequacy.[[33]](https://www.foundmyfitness.com/topics/omega-3#bibid-doi-10-1093-ajcn-nqz161) The Food and Nutrition Board of the National Academies of Medicine focuses on an adequate intake of ALA because it can be converted to EPA and DHA. However, the recommended amounts are conservative at only 1.6 and 1.1 grams per day for men and women, respectively. While these amounts are presumed to represent approximately 500 milligrams of EPA and DHA,[[34]](https://www.foundmyfitness.com/topics/omega-3#bibid-doi-10-3810-pgm-2013-11-2717) the conversion process is inefficient and varies greatly in humans (perhaps as low as 10 percent converted).[[35]](https://www.foundmyfitness.com/topics/omega-3#bibid-doi-10-1097-00075197-200203000-00002) How a person's omega-3 blood concentration responds to intake depends on multiple factors, including individual baseline concentration, body weight, quantity consumed, genetic differences in fatty acid metabolism, sex, age, and in the case of supplements, dose and formulation.[[36]](https://www.foundmyfitness.com/topics/omega-3#bibid-doi-10-1155-2013-464921)[[33]](https://www.foundmyfitness.com/topics/omega-3#bibid-doi-10-1093-ajcn-nqz161) In one study, triglyceride formulations increased the Omega-3 Index 1 percent more than ethyl ester formulations of the same dose.[[33]](https://www.foundmyfitness.com/topics/omega-3#bibid-doi-10-1093-ajcn-nqz161) This may be partly explained by the presumably increased bioavailability of triglyceride forms over ethyl esters (shown by some studies but not others).[[22]](https://www.foundmyfitness.com/topics/omega-3#bibid-doi-10-1016-j-plefa-2010-06-007)[[37]](https://www.foundmyfitness.com/topics/omega-3#bibid-doi-10-1186-1476-511x-13-99) In addition, supplemental omega-3s are subject to oxidation, so product quality and/or oxidation status may factor in as well.[[38]](https://www.foundmyfitness.com/topics/omega-3#bibid-doi-10-1159-000446024) Optimal omega-3 intake for most adults To predict how much supplemental EPA and DHA are required to raise the Omega-3 Index from 4 to 8 percent, researchers analyzed data from more than 1,400 participants across 14 intervention studies. The mean duration of supplementation was 13.6 weeks, and the mean dose was 1,983 milligrams of either a dietary supplement or a prescription product. The researchers estimated that the dosage required to increase the Omega-3 Index into the recommended range of 8 percent or greater ranged from 1,750 to 2,500 milligrams (1.75 to 2.5 grams) per day.[[33]](https://www.foundmyfitness.com/topics/omega-3#bibid-doi-10-1093-ajcn-nqz161) Omega-3 fatty acid tissue incorporation varies A person's omega-3 status varies depending on several factors, including genetics, diet, gender, and age and may not be reflective of intake.

    read the source →
  • Examine.com

    “Krill Oil benefits, dosage, and side effects”

    Supplementation of Krill oil tends to be in the range of 1-3g daily (overall oil weight), which has been used in the clinical trials of krill oil supplementation. If supplementing in accordance with the omega-3 content, the omega-3 content that is supplemented from krill oil should be equal to approximately 2/3rds that used with basic fish oil supplementation to account for the increased absorption. If one were to normally supplement 1000mg EPA plus DHA, then 660mg of EPA and DHA from krill oil would be equivalent. Supplements Demystified: Get Our Unbiased, Evidence-Based Guide Uncover the truth about popular supplements like creatine, turmeric, garlic, zinc, melatonin, and more. Plus, we'll debunk myths surrounding multivitamins, testosterone boosters, and immune supplements. Become a savvy supplement shopper. Learn how to spot the hidden signs of low-quality products and save money by avoiding ineffective supplements. Demystify scientific studies. Develop the skill to sift through the jargon and make empowered decisions for your health. Transform your lifestyle with easy-to-apply, practical health tips. Bonus PDF: Also get Examine's Top 10 Most Popular Study Summaries over the past 12 months, covering gluten-free eating, calorie and time restricted eating, cognitive health, ashwaganda, muscle building, and more. Show me what works Examine Database: Krill Oil Show Conditions Filters Expand AllCollapse All

    read the source →

How to use

2 soft gels daily with food. Take consistently for 8–12 weeks to see full mood benefits.

Who it's for

Anyone experiencing low mood, anxiety, brain fog, or inflammatory conditions. EPA is specifically mood-supportive.

Get Nordic Naturals Ultimate Omega

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Related topics

Mental HealthBrain FogInflammation

This product supports these goals.

Mental Clarity
Reduce Anxiety
Reduce Inflammation

Wellav8 may earn a commission from products linked on this page. All products are independently selected based on our five-point standard. No brand pays for placement. These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.