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Immune Support
Wellav8 Standard — 4.8/5

Thorne Zinc Picolinate

“The immune mineral most people are missing.”

$14supplement

30mg zinc in picolinate form — the most bioavailable zinc chelate. Supports immune function, wound healing, testosterone production, and taste/smell. NSF Certified. Over 2 billion people worldwide are zinc deficient.

Our assessment

Purity5/5
Efficacy5/5
Sourcing4/5
Value5/5
Transparency5/5

Purity & verification

Verification & Testing

NSF Certified for Sport
Third-party tested
GMP certified
Heavy metals free
No proprietary blends
COA available
View Certificate of Analysis →
Gluten-freeSoy-freeDairy-free

Why we chose it

Picolinate form — highest bioavailability

NSF Certified for Sport

Clinical 30mg dose

Exceptional value at $14

Key ingredients

Zinc (as zinc picolinate)

The science

Zinc is a cofactor for over 300 enzymes. It’s essential for T-cell function, neutrophil activity, and natural killer cell cytotoxicity. Clinical trials show zinc supplementation reduces cold duration by 33%.

Evidence

From the sources we read every week for our concierge recommendations.

  • Rhonda Patrick

    “ FoundMyFitness Topic - Zinc ”

    A study in 18 women between the ages of 18 and 40 years who consumed a total of 60 milligrams of zinc per day for 10 weeks found that the participants’ erythrocyte copper-zinc dismutase, or ESOD, levels decreased 47 percent compared to pre-supplementation levels.[[203]](https://www.foundmyfitness.com/topics/zinc#bibid-doi-10-1093-ajcn-49-1-145) ESOD is a copper- and zinc-dependent enzyme that converts an oxygen radical to hydrogen peroxide and can be used to measure copper status.[[204]](https://www.foundmyfitness.com/topics/zinc#bibid-doi-10-1007-bf01846029)[[205]](https://www.foundmyfitness.com/topics/zinc#bibid-doi-10-1093-ajcn-61-3-621s) Interestingly, a study in four people who used zinc-containing denture creams found that the use of two tubes of cream per week containing 17 to 34 milligrams of zinc per gram of cream caused copper deficiency.[[206]](https://www.foundmyfitness.com/topics/zinc#bibid-doi-10-1212-01-wnl-0000312375-79881-94) Furthermore, 47 healthy participants who took 50 milligrams of elemental zinc or a placebo three times a day for six weeks reported symptoms including headaches, abdominal cramps, nausea, loss of appetite, and vomiting, but none of the participants experienced reduced serum copper levels.[[207]](https://www.foundmyfitness.com/topics/zinc#bibid-doi-10-5694-j-1326-5377-1987-tb120232-x) However, the study did not measure ESOD activity to assess copper status, which may be more clinically relevant than serum copper levels. Zinc supplementation and drug interactions Zinc supplementation can reduce the absorption of antibiotics such as cephalexin and tetracycline.[[208]](https://www.foundmyfitness.com/topics/zinc#bibid-doi-10-1007-bf00614009) A study found that 50 milligrams of elemental zinc decreased the bioavailability of cephalexin, but the drug’s bioavailability was not notably altered if the zinc was administered three hours after cephalexin dosing.[[209]](https://www.foundmyfitness.com/topics/zinc#bibid-doi-10-1111-j-1365-2125-2011-04098-x) Additionally, zinc co-administered with ciprofloxacin (an antibiotic) or atazanavir and ritonavir (antiviral drugs used in the treatment of HIV and AIDS) decreased the drugs’ bioavailability.[[210]](https://www.foundmyfitness.com/topics/zinc#bibid-doi-10-1128-aac-33-11-1841)[[211]](https://www.foundmyfitness.com/topics/zinc#bibid-doi-10-1128-aac-00357-13) When ciprofloxacin and zinc administration was separated by at least two hours, the bioavailability of ciprofloxacin was not affected. Therapeutic metal-chelating agents such as diethylenetriamine pentaacetate, a drug used to expedite the elimination of plutonium, americium, or curium following acute radiation exposure, can cause zinc deficiency. (Source: REMM) Zinc supplementation Zinc supplements are typically sold as varying forms of water-soluble salts such as zinc gluconate, zinc sulfate, zinc acetate, zinc citrate, zinc oxide, and zinc picolinate. Each of these supplemental forms contains different percentages of elemental zinc: zinc gluconate (14 percent), zinc sulfate (23 percent), zinc acetate (30 percent), zinc citrate (31 percent), zinc oxide (80 percent), and zinc picolinate (21 percent).[[100]](https://www.foundmyfitness.com/topics/zinc#bibid-doi-10-3945-jn-113-181487) In other words, 220 milligrams of zinc sulfate contains 50 milligrams of elemental zinc.

    read the source →

How to use

1 capsule daily with food. Take away from calcium and iron supplements (they compete for absorption).

Who it's for

Anyone who gets sick frequently, has slow wound healing, or eats a plant-heavy diet (phytates reduce zinc absorption).

Get Thorne Zinc Picolinate

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Related topics

ImmuneSkin

This product supports these goals.

Immune Support
Hormone Balance
Skin Health

Wellav8 may earn a commission from products linked on this page. All products are independently selected based on our five-point standard. No brand pays for placement. These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.